Patient education: Antinuclear antibodies (ANA) (Beyond the Basics)
May 19, 2025 · A positive test for ANA may help determine the specific type of autoimmune disease that is affecting a patient. A negative test for ANA can assist health care providers by decreasing the …
Systemic lupus erythematosus in adults: Clinical manifestations and ...
Feb 12, 2025 · In addition, Epstein-Barr virus infection may lead to a positive ANA [84,85]. Human parvovirus B19 can cause flu-like symptoms and hematologic abnormalities such as leukopenia and …
Diagnosis and differential diagnosis of rheumatoid arthritis
Use in patients with a low pretest probability of rheumatoid arthritis – We suggest against testing patients with joint pain in the absence of synovitis (eg, nonspecific arthralgias, fibromyalgia, OA) …
Patient education: Antinuclear antibodies (ANA) (Beyond the Basics)
Jun 23, 2021 · A positive test for antinuclear antibodies (ANA) may assist health care providers in establishing the diagnosis of an autoimmune disease and may help determine the specific type of …
Measurement and clinical significance of antinuclear antibodies
Apr 4, 2024 · This topic will review the clinical utility and limitations of ANA testing, techniques for detecting ANAs, and interpretation of ANA testing, including significance of staining patterns and …
Antiphospholipid syndrome: Diagnosis - UpToDate
Sep 27, 2024 · Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to …
Systemic lupus erythematosus in adults: Clinical ... - UpToDate
Feb 12, 2025 · In addition, Epstein-Barr virus infection may lead to a positive ANA [84,85]. Human parvovirus B19 can cause flu-like symptoms and hematologic abnormalities such as leukopenia and …
Antibodies to double-stranded (ds)DNA, Sm, and U1 RNP
Oct 24, 2025 · INTRODUCTION Selected antinuclear antibodies (ANAs), including anti-double-stranded deoxyribonucleic acid (dsDNA) and anti-Sm, are highly specific for diagnosing systemic lupus …
The anti-Ro/SSA and anti-La/SSB antigen-antibody systems
Oct 24, 2025 · Anti-Ro/SSA antibodies may be the only autoantibodies present in a subset of patients with antinuclear antibody (ANA)-negative SLE. Additionally, anti-Ro/SSA antibodies (with or without …
Mixed connective tissue disease - UpToDate
Oct 13, 2025 · INTRODUCTION Mixed connective tissue disease (MCTD) is a systemic rheumatic disease characterized by clinical features of systemic lupus erythematosus (SLE), systemic sclerosis …