Due to its structural characteristics, CD2 is a member of the immunoglobulin superfamily; it possesses two immunoglobulin-like domains in its extracellular portion.

Jun 9, 2020 · The glycoprotein CD2 is a costimulatory receptor expressed mainly on T and NK cells that binds to LFA3, a cell surface protein expressed on e.g., antigen-presenting cells.

CD2 is a transmembrane molecule belonging to the immunoglobulin supergene family that plays a crucial role in T-cell activation, cytolysis, apoptosis, and cytokine production.

Nov 13, 2025 · CD2 (CD2 Molecule) is a Protein Coding gene. Diseases associated with CD2 include Mastocytosis, Cutaneous and Extracutaneous Mastocytoma. Among its related …

Jul 25, 2025 · CD2 is a protein found on the surface of certain immune cells, acting as a marker. These specialized proteins play a part in how cells interact and respond within the immune …

Jul 4, 2025 · Exogenous CD2 supplementation enhances the ability of CAR-T cells to form high-quality synapses, reduces T-cell exhaustion, and increases sustained antitumor efficacy.

Explore the CD2 gene, its function, expression, and role in immune responses. Learn about CD2 signaling, deficiency, and its potential implications in various diseases.

The glycoprotein CD2 is a costimulatory receptor expressed mainly on T and NK cells that binds to LFA3, a cell surface protein expressed on e.g., antigen-presenting cells.

We found that CD2 localized to the outer edge of the mature immunological synapse (IS), with cellular or artificial APC, in a pattern we refer to as a “CD2 corolla”. The corolla captured …

Aug 5, 2022 · The CD2 glycoprotein on T cells is an activating receptor in the immunological synapse between T cells and antigen-presenting cells (APCs) needed for optimal TCR …