The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca 2+ ion channel found in neurons. [3][4] The NMDA …

Dec 11, 2022 · The N-methyl-D-aspartate (NMDA) receptor is a glutamate receptor, the human brain's primary excitatory neurotransmitter. It plays an integral role in synaptic plasticity, a …

Nov 24, 2024 · NMDA receptors belong to the family of ionotropic glutamate receptors, distinct from G protein-coupled receptors (GPCRs). These receptors play a pivotal role in regulating …

Jul 19, 2025 · NMDA drugs are substances that interact with N-methyl-D-aspartate receptors in the brain, modifying the flow of information between nerve cells. This action influences a wide …

Here, we will review the relationship between NMDA receptor structure and function, the diversity and significance of NMDA receptor subtypes in the CNS, as well as principles and rules by …

N-methyl-D-aspartic acid, or N-methyl-D-aspartate (NMDA), is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the …

Aug 2, 2023 · Since the discovery of N-methyl-D-aspartate ionotropic glutamate receptors (NMDARs) four decades ago, substantial efforts have been made to dissect their multifaceted …

Jun 18, 2025 · NMDA receptors are a subtype of glutamate receptor widespread throughout the central nervous system. They regulate the strength of connections between neurons, a …

NMDA receptors (NMDARs) are glutamate-gated cation channels with high calcium permeability that play important roles in many aspects of the biology of higher organisms.

Dec 1, 2023 · N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated ion channels widely expressed in the central nervous system that play key role in brain development and …