Researchers developed a new machine learning method that, given a relevant amino acid sequence, can automatically predict the location of a protein in any human cell line down to the single-cell level ...

Sarika Kondra and her co-author's TSR-based method represents a major advancement in protein structure analysis, integrating ...

This valuable study presents an analysis of evolutionary conservation in intrinsically disordered regions, identified as key drivers of phase separation, leveraging a protein language model. The ...

Yet, despite more than 20 years of study, the sweet receptor’s precise architecture remained elusive, even as scientists ...

Perform pairwise secondary structural alignments of proteins using the US-align (TM-align) algorithm and generate an accompanying dendrogram to visualise the structural relationship between them.

Molecular biology has transitioned to a new era where precise genetic manipulation plays a critical role in research, medicine, and biotechnology. Among the vital tools in this field are cloning ...

Integral membrane protein structure determination traditionally requires extraction ... After a best model was achieved, the particles were further sorted by a 3D classification without alignment ...