This research highlights the role of exons in mental illnesses, offering new perspectives on genetic factors that influence ...

Alternative splicing (AS) is a fundamental regulatory mechanism in messenger RNA (mRNA) processing, and abnormal splicing is a major cause of genetic disorders. To understand the genetic ...

By altering the expression of key metabolic genes, alternative splicing generates diverse mRNA transcripts, which enhance protein diversity and metabolic flexibility. This regulatory mechanism ...

[Cincinnati Children’s] While cataloging all possible neoantigens produced from alternative mRNA pathways, the team found that in patients with melanoma, the amount of splicing neoantigens ...

or mRNA, transcript that encodes protein. Alternative splicing is a process by which a cell can select which of those protein-coding parts to include in the resulting RNA or protein. Alternative ...

or mRNA, transcript that encodes protein. Alternative splicing is a process by which a cell can select which of those protein-coding parts to include in the resulting RNA or protein. Alternative ...

In the most recent study, Lo followed up this observation from her previous paper to investigate the role of oncogenic KRAS in eliciting alternative mRNA splicing that might further drive ...

Fujian Provincial Key Laboratory of Plant Functional Biology, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, China Alternative splicing ... Taken together, it is clear ...

Aberrant alternative splicing of pre-mRNA is an emerging cancer hallmark. Many cancer-associated genes undergo alternative splicing to produce multiple isoforms with diverse or even antagonistic ...

Alternative splicing generates splicing variants of sarcomeric genes ... we ablated RBM24 in human embryonic stem cells and uncovered that RBM24-mediated exon 6 inclusion in ACTN2 mRNA transcripts ...