Paris: Sanofi has received orphan drug designation from the US Food and Drug Administration (FDA) for rilzabrutinib, a novel, ...

Rilzabrutinib granted orphan drug designation in the US for sickle cell disease <li /> Fourth orphan drug designation for rilzabrutinib ...

Researchers evaluated the use of ultrawide field swept-source OCT-A to evaluate retinal vasculature in patients with sickle cell retinopathy.

People with sickle cell disease are immunocompromised, which means they have an increased risk of infection. For this reason, immunizations are an important part of complete sickle cell care. This ...

Early diagnosis and appropriate treatment of neurological complications of sickle cell anemia require hematological and neurological expertise. Stroke prevention guidelines for sickle cell disease ...

ABSTRACT: Sickle cell anemia (SCA) is a prevalent genetic disorder primarily affecting individuals of African descent and populations in malaria-endemic regions, with significant global public health ...

Conclusion Lipid metabolism disorders, especially hypocholesterolemia and hypertriglyceridemia, are linked to clinical events observed in SCA, suggesting they play a relevant role in the ...

Herein, we present the coexistence of sickle cell disease and autoimmune hemolytic anemia in two adolescent patients, focusing on their pathophysiology, diagnosis, clinical management, and outcomes.

Sickle cell anemia may qualify as a disability for people experiencing severe symptoms, allowing access to benefits. However, eligibility depends on how the condition affects daily life.

A well-coordinated, multicenter, prospective longitudinal cohort study of sickle cell disease in Africa will improve our understanding of the pathophysiology ... to treat anemia and prevent ...

Sickle-cell disease is an inherited blood disorder that can cause symptoms during early childhood and throughout life. It is characterized by episodes of severe pain. Sickle cell disease can also ...