This RNA-containing complex can then inhibit transcription of an mRNA molecule that has a sequence complementary to its RNA component. Inside the eukaryotic nucleus, the nucleolus is the structure ...

Vaccines using mRNA are currently being studied for a wide range of diseases, including cancer, cardiovascular disease, ...

Messenger RNA carries genetic information from DNA in the highly ... The journey of mRNA begins in the cell nucleus, where it is synthesized through a process called transcription: Through this ...

COVID-19 brought messenger RNA (mRNA) into the global spotlight ... and how these innovations are shaping the future of genetic medicine. Additionally, mRNA production via in vitro transcription is ...

UC Irvine scientists developed bioluminescent RNA tags, "tiny guiding lights," using luciferase to track RNA in real-time, ...

BioNTech is advancing mRNA therapies for influenza, tuberculosis, and various cancers while also exploring circular RNA and self-amplifying RNA (saRNA) technologies to boost durability and reduce ...

C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic information from DNA to messenger RNA (mRNA). As there are more than 700 ...

More information: Tanja Bhuiyan et al, TAF2 condensation in nuclear speckles links basal transcription factor TFIID to RNA splicing factors, Cell Reports (2025). DOI: 10.1016/j.celrep.2025.115616 ...

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology.

Anti-aging biotech NewLimit plans to push a liver-rejuvenating mRNA medicine into the clinic with the aid of a ...

This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...