Paraneoplastic syndromes affect multiple organs and are a central cause of mortality in cancer patients. In this issue, Cong et al ( 2025) report an inflammatory gut-kidney axis mediating systemic ...

Engineered extracellular vesicles incorporating a viral fusogenic protein and bacterial intein enable efficient intracellular delivery of therapeutic proteins and RNA.

The study adds to other work that has implicated pathogen-derived processes in the selective recruitment of vesicles to the pathogen-containing vacuole, based on the content of the cargo. The ...

Examples of organelles include the nucleus, the endoplasmic reticulum, the Golgi, mitochondria, vacuoles or lysosomes ... Cryo-ET reveals hemifused vesicles containing a hemifusion diaphragm ...

The National Medical Commission (NMC) has published the NEET syllabus for 2025 on its official website, nmc.org.in. Candidates planning to appear for the NEET UG exam in 2025 can find the updated ...

Here, we describe the isolation and structure determination of proteins in membrane vesicles derived directly from cells. Structures of the ion channel Slo1 from total cell membranes and from cell ...

In intestinal epithelial cells abutting the lumen of the gut, pinocytosis of IgG from the tissues allows internalization into intracellular acidic vesicles. There, it binds FcRn and is transported ...

Given the contribution of EC-derived EVs to atherosclerosis, this model represents the first in vivo murine approach to tracking intercellular EC-EV communication within the plaque. It provides an ...

Vesicles are small blisters that can appear on your skin. They can be a symptom of a medical issue or a sign of tissue injury. Some conditions, like contact dermatitis or cold sores, may not ...

Transformation into vesicles was shown to occur independent of the initial anionic counterparts and was driven by salt-bridge interactions between guanidinium groups of arginine residues and ...

The proteins are clustered in one vesicle and then another vesicle and then finally handed off to the lysosome. We think NU-9 targets something in the early stage of that relay, but we don’t ...