In neurodegenerative diseases such as Alzheimer's or Parkinson's, proteins accumulate in the body's cells, fold incorrectly and clump together to form larger aggregates. Normally, cells are able to ...

In neurodegenerative diseases such as Alzheimer's or Parkinson's, proteins accumulate in the body's cells, fold incorrectly ...

Department of Endocrinology and Metabolism, Affiliated Hospital of Qingdao University, Qingdao 266003, P. R. China Qingdao Key Laboratory of Thyroid, Diseases, Medical Research Center, Qingdao 266555, ...

Briefly, high resolution confocal images containing the LC3 (red and green) and CTSD (blue ... for WB with antibodies directed against several marker proteins in the autophagy pathway, representing ...

Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, ...

Department of Ophthalmology, Tongji Hospital Affiliated with Tongji University, Shanghai 200065, People’s Republic of China ...

(2) Autophagy Modulation: Certain EOs activate autophagy via the p53 signaling pathway, leading to the upregulation of hepatic LC3-Ⅱ, which facilitates the clearance of necrotic cells. Conversely, ...

First, current detection modalities—including LC3-II/p62 immunoblotting and transmission ... systematic investigation into the autophagy-related pathways in DM. (4) Poor bioavailability and stability ...