which in turn bind to regulatory sites in the DNA that effectively block RNA polymerase binding (Figure 3). The control of gene expression in eukaryotes is more complex than that in prokaryotes.

Background and aims Quantifying systemic inflammation (SI) in acutely decompensated cirrhosis (ADC) is of major importance ...

Northwestern University biophysicists have developed a new computational tool for identifying the gene combinations ...

classification (Figure 1B). Clusters 7, 8, 11, and 14 were not associated with a FAB subtype but had distinct gene-expression profiles. Overall survival, event-free survival, and relapse rates ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

This valuable study investigates how stochastic and deterministic factors are integrated during cellular decision-making, particularly in situations where cells differentiate into distinct fates ...

This temperature regulation of gene expression produces rabbits with a ... causing the fur color to be white (Figure 1). Meanwhile, in the rabbit's extremities (i.e., the ears, tip of the nose ...

Unlike existing treatments for Alzheimer’s that target unhealthy protein deposits, the new approach developed at UC San Diego ...

Gene expression leading to alterations in the DNA caused by asbestos exposure may explain the development of malignant ...

But the grammar of CREs has been hard to figure out, “with no straightforward ... for designing genetic switches that precisely tune gene expression for novel applications, such as ...

Sizeable differences in gene expression means and ratios—based solely upon where genes are located on a plasmid (gene syntax)—have been discovered by researchers at Dartmouth College.

It also includes searching for mutated genes that confer a unique vulnerability to cancer cells and studying gene expression patterns that are associated with mutation status across all tumor types. A ...