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Discovered decades ago in the jellyfish Aequorea victoria as a primary feature of bioluminescence 1, a green fluorescent protein (GFP) is a commonly utilized fluorescent dye for in vivo imaging.
The present-day in vivo imaging community has been a key benefactor from the discovery of GFP, the characterization and cloning of the protein 8, along with the extension of the fluorescent ...
The first use of GFP for in vivo imaging, visualized cancer cells growing in athymic nude mice in our laboratory. 21 Cancer cells were stably transfected with GFP and were transplanted into ...
While GFP and its derivatives are commonly used ... improving the accuracy and reliability of in vivo imaging techniques. The researchers used a series of molecular biology techniques to develop ...
Hemodynamic occlusion introduces a spatially heterogenous confound to activity measurements using two-photon and widefield imaging in mouse cortex, and needs to be taken into consideration when ...
“We have moved beyond that,” says Alexandra De Lille, Ph.D., director of technical applications for in vivo imaging at Perkin­Elmer. Dr. De Lille describes two major trends driving the in ...
lead author of an Osaka University study that aimed to design acid-tolerant monomeric GFP that is practically applicable to live-cell imaging in acidic organelles. “In the current study, we developed ...
Gao and his colleagues report their new in vivo 3D-printing technique in the ... the monomers of the polymer they wanted to print, an imaging contrast agent that would reveal when the crosslinking ...
Using an innovative in vivo imaging tool to capture functional activity in mouse models of TMJ injury and inflammation, the discovery could pave the way for more effective treatments for the ...