The Swiss drugmaker says the safety and efficacy of zosurabalpin will be investigated in a study involving 400 patients with ...

Flaxseed oil, flaxseeds, and chia seeds are a better source of ALA than walnuts, while seafood, like salmon, sardines, and ...

Natural products are among the most promising candidates for the development of new drugs. However, due to their structural complexity, they are often difficult to access.

We found that arginine limitation in pancreatic tumors perturbs saturated and monounsaturated fatty acid synthesis by suppressing the lipogenic transcription factor SREBP1. Synthesis of these fatty ...

The scientists then treated the mice with a drug that blocks fatty acid synthesis, and the cancer cells in brain tissue grew at half-speed. (The breast cells in the mammary fat continued to grow ...

They lower serum LDL-C levels by competitively inhibiting the enzyme HMG-CoA reductase, which transforms HMG-CoA to mevalonate during cholesterol synthesis ... 1α (PGC-1α), sirtuin 1 (SIRT1), fatty ...

Fatty acids that are mobilized from TGs provide metabolic energy ... This subdomain is targeted by Lro1 and is known to expand in response to excess phospholipid synthesis (Barbosa et al, 2019; Witkin ...

As the first fatty acid to be produced during initial fatty acid synthesis, palmitic acid is a primary part of an animal’s body. Additionally, in humans, palmitic acid has been seen to make up ...

FAS and SREBP-1c mRNA levels were strongly and positively correlated with each other and inversely correlated with hepatic TGs, suggesting that impaired TG export is a potent inhibitor of fatty acid ...

aDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, Soochow University, 188 Shizi Street, Suzhou, Jiangsu 215006, China ...