17 18 19 The advantages and limitations of these various viral vector-based systems in biological research are discussed elsewhere. 7 However, episomal vectors are being considered for use in ...

The benefit of maintaining the original genome of cells being reprogrammed outweighs the fact that the episomal vector approach is both time- and labor-intensive, says Guo-li Ming, Ph.D ...

The benefit of maintaining the original genome of cells being reprogrammed outweighs the fact that the episomal vector approach is both time- and labor-intensive, says Guo-li Ming, Ph.D ...

Generating human induced pluripotent stem cells (hiPSCs) has attracted a great deal of attention due to the cells’ resulting differentiation potential and the elimination of the ethical hurdles ...

They then generated giant panda iPSCs (GPiPSCs) using a non-integrating episomal vector reprogramming method. The study revealed that the GPiPSCs exhibit the capability to differentiate into ...

In this study we developed an optimized single Episomal vector bearing multiple interspersed genes. This single entity plasmid electroporated into fibroblasts and cultured in low oxygen tension (4%O2) ...