coli strain that gives high-quality plasmid DNA (for example ... 10 μl of each miniprep with the appropriate pair of restriction enzymes and separating the fragments by electrophoresis through ...

This is an important study utilizing innovative CRISPR based approaches demonstrating the role of the KLF family of transcription factors in the post natal maturation of cortical projection neurons.

This new service delivers clinical-grade plasmid DNA production from cell bank to batch release in three months. This can help accelerate the development of gene and cell therapies. Located to serve ...

Fragmentomics encompasses the analysis of fragment lengths, end motifs ... Mathematical modeling of cell-free DNA fragmentation to map chromatin landscapes in health and cancer [abstract]. In: ...

Furthermore, GAF-dependent chromatin openness responded coordinately to population density changes. Fragment mutagenesis abolished henna promoter activity due to the dysfunction of the GAF-binding ...

Using a combination of cell-based and mouse models, the authors provide compelling evidence showing that arginine restriction in the microenvironment disrupts lipid homeostasis in PDAC, resulting in ...

"China has already decided to construct a dam which will have the capacity to produce 60,000 MW of electricity. This is not going to be a dam, but a water bomb to be used against India and other lower ...

In this study, we constructed a novel MVA reverse genetics system consisting of five plasmids covering the full viral genome from chemically synthesized DNA ... using restriction enzymes. A ...

For example, a comprehensive structure–function analysis of the ubiquitin-conjugating enzyme UBE2S required ... Generation of optimized DNA linker sequences. To generate optimized homology sequences ...

Restriction Enzyme Map Generator: Build a tool that identifies restriction enzyme cut sites in a DNA sequence and generates a visual map. Genetic Code Translator: Create a tool that translates DNA ...