A specialized model used by researchers is becoming a valuable tool for studying human brain development, diseases and ...

From a meeting that celebrates basic research and being "first," a look at 3 data sets on therapies that would break new ...

A newly developed radiolabeled antibody that targets the cancer antigen ... mouse model. Lead candidate anti-IL13Rα2 antibody KLG-3 validated highly specific target binding in human glioblastoma ...

Describes the nature of a clinical study. Types include: Observational study — observes people and measures outcomes without affecting results. Interventional study (clinical trial) — studies new ...

The presentation was titled “A Phase 1, Open-label, Single Center Study of an Autologous Fully humanized Anti-CD19 Chimeric Antigen Receptor T Cell (CD19 CAR T) Therapy in Subjects with Non ...

A multi-institutional team developed a chimeric antigen receptor (CAR ... KG2032 CAR T cells displayed strong anti-AML effects in a mouse model, and CAR natural killer cells showed similar ...

Scientists at the Allen Institute, a research center in Seattle, then sliced that piece of the mouse’s brain into more than 25,000 layers, each a tiny fraction of the width of a human hair ...

While there are notable differences between mouse and human brains, many organizational principles remain conserved across species. The research focused upon a part of this region called the ...

Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing their ability to infiltrate solid tumours.

Chimeric antigen receptor (CAR) T-cell therapy has revolutionised the treatment of haematological malignancies and has demonstrated efficacy in early trials for solid tumours, neurological and ...