The transition from preclinical development to clinical trials is a critical, with approximately 89% of drugs failing. Nearly half of these failures stem from unexpected and unmanageable human ...

Genetic engineering technologies allow for the creation of custom-made cells that can have transformative effects on human health. This is best exemplified by chimeric antigen receptor (CAR ...

A specialized model used by researchers is becoming a valuable tool for studying human brain development, diseases and ...

Yet, despite more than 20 years of study, the sweet receptor’s precise architecture remained elusive, even as scientists ...

Apr. 25, 2025 — Chimpanzee naive pluripotent stem cells (PSCs) can now be grown in cellular cultures, reveals a recent study. They successfully created chimpanzee early embryo models, called ...

Here, they are captured by the APCs, which then cause apoptosis among the antigen-specific T cells ... or direct interaction with specific IgE, Fc receptors on Langerhans cells, mast cells ...