Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, ...

Scientists have uncovered more than 20 genes whose mutations cause familial forms of Parkinson's disease. One of these genes is known as VPS13C, and mutations in this gene may contribute to the ...

Free breakfast clubs are to launch at 750 schools across England next week but teachers have voiced concerns that government funding for the scheme will not meet the cost. From Tuesday ...

No matter what your morning routine is, chances are your household is busy first thing and making a healthy breakfast when you're trying to get out the door is impractical some days. Grabbing a frozen ...

The researchers measured nearly 40 percent less LAMP2, LIMP-2, GCase, and cathepsin B in the knockout cell lysosomes. These cells also cleaved prosaposin and progranulin less effectively. Progranulin ...

Berkshire Hathaway, Inc. is a holding company, which engages in the provision of property and casualty insurance and reinsurance, utilities and energy, freight rail transportation, finance ...

Fast food is America's go-to for a quick and easy meal, and for a quick breakfast, it's hard to beat a fast food sandwich. They offer the ideal combination of convenience, comfort, and are undeniably ...

Naga Munchetty kept her distance from her BBC Breakfast co-star Charlie Stayt and show editor as she left the studios in Manchester amid a rumoured feud and bulling row. The 50-year-old and ...

is mainly caused by homozygous or compound heterozygous biallelic pathogenic mutation of the cathepsin K (CTSK) gene. The cohort included eight patients (four males and four females) with a mean ...

After further analysis, the researchers found the drug relies on lysosomes, which are one of the cells’ major recycling centers, and on an enzyme called cathepsin B. In Alzheimer’s disease, this ...

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes.

Insmed Inc. has divulged cathepsin C (dipeptidyl peptidase I, DPP1) inhibitors reported to be useful for the treatment of amyotrophic lateral sclerosis, asthma, metastatic cancer, chronic ...