Researchers found that chronic sucralose exposure in male rats disrupted reproductive hormones, damaged sperm, and impaired ...

After further analysis, the researchers found the drug relies on lysosomes, which are one of the cells’ major recycling centers, and on an enzyme called cathepsin B. In Alzheimer’s disease, this ...

The cast of the iconic 1980's film "The Breakfast Club" – Molly Ringwald, Ally Sheedy, Judd Nelson, Anthony Michael Hall and Emilio Estevez – reunited for the first time in 40 years during a ...

It also uses the help of an enzyme called cathepsin B, which helps digest unwanted proteins. "Cells have two important 'junk compartments': the lysosome and the proteasome," Silverman said.

After further analysis, the researchers found the drug relies on lysosomes, which are one of the cells' major recycling centers, and on an enzyme called cathepsin B. In Alzheimer's disease ...

After further analysis, the researchers found the drug relies on lysosomes, which are one of the cells' major recycling centers, and on an enzyme called cathepsin B. In Alzheimer's disease ...

Cathepsin B (CTSB), a key cysteine protease ... allow procathepsin B to be recognized by the mannose 6-phosphate receptor, directing it towards the lysosome for translocation (3). In the acidic ...

Endosomes and lysosomes form giant structures in the periphery of the ... Supplementary Fig. 11. Magic Red Cathepsin B staining in GV and MII oocytes showed higher cytoplasmic signals but similar ...

Membrane proximal lysosomes are the major vesicles responsible for calcium ... Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and ...

Lysosomes are involved in protein turnover and removing misfolded species, and their enzymes have the potential to offset the defect in proteolytic clearance that contributes to the age-related ...

Given that cancer cell lysosomes often exhibit high levels of the enzyme 'Cathepsin B,' responsible for protein degradation, the micelles specifically target these lysosomes. Once inside the lysosome, ...