Despite decades of research, its full behaviour remained a mystery, mainly because the protein is heavily glycosylated ... adding significant complexity to its structure . Using molecular ...

FVIII, the blood clotting protein missing in hemophilia A, adopts multiple shapes, making it more likely to be targeted by ...

AfCycDesign: Cyclic offset to the relative positional encoding in AlphaFold2 enables accurate structure prediction ... transition metal binding sites in proteins. It integrates geometric and ...

Protein 4.1R in red blood cells has multiple binding sites for membrane and skeletal proteins and plays a critical role in maintaining cell morphology and membrane mechanical properties 1. The ...

The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships not only of proteins, but “all of life’s molecules”, according to its ...

Thousands of these four components encapsulate mRNA, shield it from destructive enzymes, and shuttle it into cells, where the mRNA is unloaded and used to make proteins. Although the concept seems ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

The second half develops topics in molecular biology and protein structure, with a view to discovering mechanisms underlying protein folding. Attention is focused on the energy flow through the ...

† Department of Oral Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States ‡ Department of Physics, University of Wisconsin, Madison, Wisconsin 53706, United States Article ...