The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release ...

New tissue-derived organoid model: A next-generation organoid model, composed of three liver cell types – adult hepatocytes, cholangiocytes, and liver mesenchymal cells – reconstructs the liver ...

Cells change their metabolic profiles in response to underlying gene regulatory networks, but how can alterations in metabolism encode specific transcriptional instructions? Here, we show that forcing ...

Over the last decades, several innovations have advanced the understanding of human biology and diseases. From the development of induced pluripotent stem ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

Model more closely replicates natural environment of the pancreas, which will be essential for studying diabetes and ...

Researchers led by Maike Sander, scientific director of the Max Delbrück Center, have developed a vascularized organoid model ...

Lab-grown organs, also known as organoids, are progressing from lab research toward clinical application. This article ...

To this end, we report the development of a disposable and compact fully 3D-printed electrochemical cell incorporated into a medical scalpel (Lab-on-a-Scalpel), aiming to promote on-site ...

Therefore, we established a 3D triple co-culture microfluidic system using human umbilical vein endothelial cells (HUVEC) together with primary rat astrocytes and neurons. Immunostaining confirmed the ...