Model more closely replicates natural environment of the pancreas, which will be essential for studying diabetes and ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

New tissue-derived organoid model: A next-generation organoid model, composed of three liver cell types – adult hepatocytes, cholangiocytes, and liver mesenchymal cells – reconstructs the liver ...

Over the last decades, several innovations have advanced the understanding of human biology and diseases. From the development of induced pluripotent stem ...

For organoid immunostaining ... the number of DCLK1-positive tuft cells significantly increased upon supplementation with either IL-4 or IL-13 (Figure 3D). The RNA-Seq analysis comparing the three ...

Neural organoids and 3D spheroids are a fast-evolving technology with enormous potential for studying brain development and ...

Researchers led by Maike Sander, scientific director of the Max Delbrück Center, have developed a vascularized organoid model ...

Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies.