Researchers from China developed a novel electrochemical biosensor, which enables the detection of aquaporin 4 (AQP4) immunoglobulin G (IgG) with high stability, a detection range of 0.1 to 80 U/mL, ...

Which of the statements below about the genetics of immunoglobulin G4-related disease (IgG4-RD) are correct? Select one of the options for each question, then submit your answers to see how well you ...

Researchers found that certain genera, including Roseburia and Alloprevotella, were associated with a particularly worse prognosis among individuals with malignant lacrimal gland tumors. Altered ...

Each 1-second increase in time to complete the 18MWT was associated with a 10% increased risk of PAH-related hospitalization or death. The 18-meter walk test (18MWT) offers clinicians an efficient way ...

Overall, 80% of patients with sinonasal IgG4-RD experienced symptom improvement, with more than half achieving complete resolution. Sinonasal involvement in immunoglobulin G4-related disease (IgG4-RD) ...

When comparing the BLI/INO group to the chemotherapy group, the 2-year OS was 63% vs 31.2%, respectively, and the 2-year DFS was 49.6% vs 22.9%, respectively. Blinatumomab (BLI) and inotuzumab ...

Systemic mastocytosis may predispose some individuals to develop vertebral fractures. A middle-aged man with lower back pain was diagnosed with systemic mastocytosis (SM), which is an extremely rare ...

Sharon Hesterlee, PhD, who previously served as chief research officer at the MDA, has been named interim president and CEO. Donald S. Wood, PhD, has retired from the Muscular Dystrophy Association ...

Fatal events occurred less frequently in patients with CLL treated with BTK inhibitors than with chemoimmunotherapy regimens. Acalabrutinib, a second-generation Bruton tyrosine kinase (BTK) inhibitor, ...

Soticlestat was not more efficient than placebo in reducing seizures in patients with Lennox-Gastaut syndrome (LGS). Soticlestat is significantly more efficient than placebo in reducing convulsive ...

Patients with identifiable amyloid deposition in the prostate had significantly more severe transthyretin (TTR) amyloid deposition in the heart compared to those without prostatic deposition. The ...

GSK3β ihibition leads to a reduction in axonal transport defects mediated by poly-Q and neuronal cell death while ERK inhibition increases these biological events. The phosphorylation of glycogen ...