UC Irvine scientists developed bioluminescent RNA tags, "tiny guiding lights," using luciferase to track RNA in real-time, ...

The RNP complex is the influenza virus’s essential package, the virus’s blueprints and a copy machine all rolled in one. The ...

K nowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions.

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...

An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification.

Much of that work happened in Canada. Messenger RNA (mRNA) are large, negatively charged molecules that are easily degraded and repelled by our cells. To coax our cells to internalize them, scientists ...

A safety analysis of mRNA vaccination in a phase 1, randomized, open-label clinical trial evaluated the safety and tolerability of three investigational HIV-1 trimer mRNA vaccines. The study ...

Moderna is currently in the very early stages of testing a bird flu vaccine using the same mRNA technology that allowed for rapid development and rollout of COVID-19 vaccines. The funds from the ...

One type of molecule that can be used to achieve that suppression is microRNA—a short RNA sequence that binds ... that a microRNA strand that represses mRNA translation is encoded within the ...

while also enhancing the translational efficiency of RNA synthesized in vitro (Goel et al., 2021; Kang et al., 2023). The mRNA produced through transcription reactions emerges as a promising platform ...

In this study, we aimed to develop a bioinformatic tool, MSI Expresso, allowing both the determination of the MSI status, the MMRd status and the detection of MSI-related transcription events using ...