First, they wanted to improve the interactions among the template RNA, the ribozyme, and the primer sequence that starts the copying. To make RNA, the ribozyme has to recognize the primer and the ...

What you see depends on how you look. For years students of cell biology were taught that a molecule called RNA was but a humble minion assisting its glamorous cousins, DNA and proteins.

The process starts with a “primer”, a short fragment of RNA (or DNA) that matches a strand of RNA (or DNA). In order to make a new strand from the existing strand, the primer needs to be extended.

These in silico primers are capable of detecting 100% of the RNA viruses included in the latest U.S National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database, an open ...

The potential of the Nanoprimer to improve treatment efficacy by avoiding liver clearance is a great opportunity to accelerate the development of RNA-based therapeutics and to bring a real benefit ...

Inosine can be incorporated into primers and probes as a universal base due to its ability ... Despite the significant advances in understanding the roles of inosine in RNA biology, several challenges ...

Get Instant Summarized Text (Gist) A new biochemical method enables mapping of RNA folding as it occurs in living cells, revealing that RNA molecules begin folding immediately during synthesis ...