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Gasdermin D (GSDMD) executes the cell death program of pyroptosis by assembling into oligomers that permeabilize the plasma membrane. Here, by single-molecule imaging, we elucidate the yet unclear ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. TP53 mutations in AML confer resistance to CAR ...

Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for ...

We report the first simulations of nonsolvent-induced phase separation (NIPS) that predict membrane microstructures with graded asymmetric pore size distribution. In NIPS, a polymer solution film is ...

This research uncovers a groundbreaking link between electron spin and proton transport in biological environment, using lysozyme as a model system. Proton transfer, vital in many life processes, is ...

This study describes the formation of a penetration ring in the rice blast fungus Magnaporthe oryzae during host cell invasion. The work provides useful insights into how the penetration ring ...

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