News

Small molecule inhibitors restore normal BRAF structure, offering insight into cancer-causing mutations
Researchers led by Université de Montréal pathology and cell-biology professor Marc Therrien have identified major structural ...
Hidden architecture: Researchers identify new molecular structure at center of chromosomes
Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...
Researchers reveal structural basis of prostaglandin D2 receptor DP1 activation and its implications for drug design
Recent breakthroughs in understanding the prostaglandin D2 (PGD2) receptor 1 (DP1) are paving the way for innovative ...
Nature3d
Unfolding the role of protein misfolding in neurodegenerative diseases
In vitro structural studies have shown that misfolding and aggregation involve a large structural rearrangement of the protein, forming cross-β amyloid-like fibrils, which seems to be the common ...
C&EN3d
Electrospun Fibers from Wheat Protein: Investigation of the Interplay between Molecular Structure and the Fluid Dynamics of the Electrospinning Process
A variety of electrospinning experiments were carried out with wheat gluten from two sources, at different solution concentrations, and with native and denatured wheat gluten to illustrate the ...
Nature3d
The structure of the ferric siderophore binding protein FhuD complexed with gallichrome
we describe the 1.9 Å resolution structure of E. coli FhuD in complex with gallichrome. FhuD adopts a novel fold and represents a new class of iron binding ABC-type transport proteins.