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A research team from POSTECH has developed a biodegradable polymer-based delivery system that efficiently transports mRNA. The study was recently published in Biomaterials.
A research team has developed a biodegradable polymer-based delivery system that efficiently transports mRNA. A research team led by Professor Won Jong Kim from the Department of Chemistry at ...
Replacing PEG with PCB in lipid nanoparticles led to potent mRNA vaccines that avoided unwanted immune responses.
Lipid nanoparticles, which delivered the mRNA COVID-19 vaccines ... Nanite takes an engineering approach to polymer-based delivery discovery, Kevlahan says. “When we started Nanite in 2021 ...
A new material developed at Cornell University could significantly improve the delivery and effectiveness of mRNA vaccines by ...
There are a variety of mRNA delivery methods that have been developed in an attempt to navigate the challenges, such as direct injection of naked mRNA, lipid-based carriers, polymers, and protein ...
Green and his team tested various materials and ultimately decided to encase a desired mRNA in a polymer-based vessel. Polymers are repetitive ... “The nanoparticle delivery system was able to create ...
Since mRNA itself is quite unstable and easily destroyed by enzymes in the body, mRNA-based therapies rely on drug delivery techniques ... cationic lipids or polymers, which form small protective ...
Lipid nanoparticles have been studied since the 1960s, but widespread use and optimization of delivery for mRNA therapeutics, including vaccines, really came to the forefront during COVID-19 ...
These findings highlight the potential of polymer-based delivery systems as a safer and more efficient alternative for next-generation mRNA vaccines and gene therapies. Professor Won Jong Kim ...