Lipofection of nondividing cells is inefficient because much of the transfected DNA is retained in endosomes, and that which escapes to the cytoplasm enters the nucleus at low rates. To improve ...

The study applied a new approach that installed hairpin internal nuclear localization signal sequences (hiNLS ... a basis for several clinical trials, and peptide-enabled RNP delivery, a hardware ...

Researchers create a magnetic nanoscale system that reversibly switches groove and ridge structures to regulate stem cell ...

In summary, our study uncovered an important circRNA-derived peptide and ... indirect protein-localization mediator of REST in a tCDYL-100–dependent way. We hypothesized that the interaction of ...

In a new study published in Cell Reports, researchers at the University of Freiburg reveal how a disordered protein segment ...

The US and Iran reported signs of progress in talks on a deal over Iran’s nuclear program after what the Iranian foreign minister described as increasingly detailed discussions. A senior US ...

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...

Europe, Iran have held sporadic direct talks since September France, Britain, Germany hold key UN sanctions card US official briefed Europeans on talks recently DUBAI/PARIS, April 24 (Reuters ...

MUSCAT, Oman (AP) — Negotiations between Iran and the United States over Tehran’s rapidly advancing nuclear program will ... this doesn’t necessarily signal a deal is imminent.