Sterols are among the most abundant lipids in eukaryotic cells, yet are synthesized through notoriously long, complex metabolic pathways. Researchers have used a novel approach to show how they ...

New research from UTHealth Houston reveals that substance use disorders accelerate biological aging in the brain through substance-specific molecular mechanisms. The study, published in Genomic ...

Advanced biliary tract cancer (BTC) includes cholangiocarcinoma, gallbladder carcinoma, and ampullary carcinoma. BTC is a ...

A key enzyme and its molecular pathway are critical to keeping activated CD8+ T cells active and away from “exhaustion”, ...

Sterols, such as cholesterol in our bodies or ergosterol in yeast cells, are among the most abundant lipids in eukaryotic ...

Rachel Wolfson, assistant professor of cell biology in the Blavatnik Institute at Harvard Medical School, began studying ...

The study highlights ALDH4A1’s role as a tumor suppressor by preventing a harmful shift in how cells produce energy.

Dynamic remodeling of the endomembrane system is a core biological process essential for maintaining cellular ...

Researchers at Novartis BioMedical Research in the US and Switzerland have identified a molecular target that may provide a ...