Sterols are among the most abundant lipids in eukaryotic cells, yet are synthesized through notoriously long, complex metabolic pathways. Researchers have used a novel approach to show how they ...

A key enzyme and its molecular pathway are critical to keeping activated CD8+ T cells active and away from “exhaustion”, ...

Sterols, such as cholesterol in our bodies or ergosterol in yeast cells, are among the most abundant lipids in eukaryotic ...

Advanced biliary tract cancer (BTC) includes cholangiocarcinoma, gallbladder carcinoma, and ampullary carcinoma. BTC is a ...

Dynamic remodeling of the endomembrane system is a core biological process essential for maintaining cellular ...

Researchers at Novartis BioMedical Research in the US and Switzerland have identified a molecular target that may provide a ...