Such transport is a constitutive phenomenon that occurs throughout the life of the neuron. Thus, the axonal cytoskeleton is best understood by considering both its anatomical organization and its ...

The neuronal actin cytoskeleton is an essential target of the multiple stimuli that act on each individual neuron, and the small Rho GTPases are essential components that link these stimuli to actin.

Each neuron receives signals and forwards them ... activates a molecular signaling pathway that directly targets the cytoskeleton. RhoA restrains axonal elongation by restricting the advancement ...

Researchers have identified a distal axonal cytoskeleton as the boundary that ... sodium and potassium ion channels and maintaining the neuron's proper organization (polarity).

Microtubules determine neuron function and survival. However, to date, little is known about the regulators of the microtubule cytoskeleton in neurons. "In addition to understanding the potential ...

The study, which has now been published in the journal Neuron, shows that an enzyme ... it controls the structure of the cytoskeleton and thus ensures that nerve cells can form the tree-like ...

This enabled Victor Macarrón-Palacios to investigate the neural cytoskeleton in his doctoral thesis. These discoveries were further complemented by biochemical techniques and the expertise and ...

They are the first authors of the study, which now appears in the prestigious journal Neuron. Until now, experts have debated the role of the centrosome. The process of growth and migration is enabled ...

The role played by the actin cytoskeleton of these compartments and how it responds in the presence of beta-amyloid peptides, the component most commonly associated with Alzheimer's, have been ...