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In an in vivo mouse model of inflammatory bowel disease (DSS-induced ulcerative colitis), onset of the pathology is delayed in Pf4 (platelet factor 4)-Cre + RalA/B flox mice. Ral GTPases could be ...
yielding mice without any detectable lysozyme biological activity in the small intestines. Keywords: Paneth Cells, Defa24iCre, Defensins, Cre-recombinase transgenic mouse model, Cre/loxP Defa24 iCre ...
Silencing hepatic Surf4 markedly reduces the development of atherosclerosis in different mouse models of atherosclerosis without causing hepatic steatosis. However, the role of Surf4 in chylomicron ...
Learn more about eLife assessments Cre-loxP technology, a cornerstone in fate mapping and ... (C) Crossing with R26-tdT mice, R26-RSR-Cre exhibits leakiness in E13.5 embryos. Scale bars, yellow 1mm.
Cre-loxP technology, a cornerstone in fate mapping and in vivo ... (B, D, F) Strategies for DreER-induced Cre expression. (C) Crossing with R26-tdT mice, R26-RSR-Cre exhibits leakiness in E13.5 ...