CR1 might also contribute to the inhibition of complement activation on a cell surface, although the main function of this receptor is in degradation of C3b associated with ICs (Figure 1).

Both the covalent attachment of C3b and the stabilization of the ... by hydroxyl-rich pathogen surfaces. A series of complement receptors mediate the recognition of opsonized cells by leukocytes ...

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In vitro, thrombomodulin binds to C3b and factor H (CFH) and negatively regulates complement by accelerating factor I–mediated inactivation of C3b in the presence of cofactors, CFH or C4b ...

15 Ribbon representation of the structure of complement C3b, as proposed by Janssen et al., 24 shows the interface region between the macroglobulin 1 domain (MG1) (light blue) and the thioester ...