The transition from preclinical development to clinical trials is a critical, with approximately 89% of drugs failing. Nearly half of these failures stem from unexpected and unmanageable human ...

A specialized model used by researchers is becoming a valuable tool for studying human brain development, diseases and ...

From a meeting that celebrates basic research and being "first," a look at 3 data sets on therapies that would break new ...

A newly developed radiolabeled antibody that targets the cancer antigen ... mouse model. Lead candidate anti-IL13Rα2 antibody KLG-3 validated highly specific target binding in human glioblastoma ...

1 Affiliated Hospital of Shandong Second Medical University, Weifang, China 2 Department of Hematology and Oncology, Shenzhen Children’s Hospital, Shenzhen, China Chimeric antigen receptor natural ...

Describes the nature of a clinical study. Types include: Observational study — observes people and measures outcomes without affecting results. Interventional study (clinical trial) — studies new ...

The presentation was titled “A Phase 1, Open-label, Single Center Study of an Autologous Fully humanized Anti-CD19 Chimeric Antigen Receptor T Cell (CD19 CAR T) Therapy in Subjects with Non ...

A multi-institutional team developed a chimeric antigen receptor (CAR ... KG2032 CAR T cells displayed strong anti-AML effects in a mouse model, and CAR natural killer cells showed similar ...