In 1998, researchers showed that mutations in a gene that codes for the protein bestrophin were responsible for causing Best macular dystrophy, a hereditary disorder that strikes during childhood ...

As part of the deal, Opus will be in charge of researching, developing, and selling new gene therapy candidates to address two adult-onset IRDs: bestrophin-1 (BEST1)-related inherited retinal ...

Opus will develop the novel gene therapy candidates to address bestrophin-1 (BEST1)-related inherited retinal diseases and rhodopsin-mediated autosomal dominant retinitis pigmentosa (RHO-adRP).