"An exciting finding was when we tried to treat the obese mice with colon inflammation by lowering their inflammation, it actually stopped the ERK pathway in the liver from activating," explains Imai.

Deficiency: If you have a vitamin B12 deficiency you will feel tired or weak, pale skin, loss of appetite, infertility and others. It can also cause balance issue, depression and poor memory.

Researchers at the Tohoku University Graduate School of Medicine have uncovered a key primary step in the hepatic ERK pathway ...

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Instead, more cells decided to turn into ectoderm tissue, the type that eventually gives rise to our nervous system. This study shows that glycolysis helps activate key signaling pathways (Wnt ...

diffuse large B-cell lymphoma (DLBCL) not otherwise specified who are ineligible for autologous stem cell transplant (ASCT). With this approval, this Columvi combination is the first bispecific ...

Columvi is a CD20xCD3 T-cell engaging bispecific antibody designed to target CD3 on the surface of T cells and CD20 on the surface of B cells. Columvi was designed with a novel 2:1 structural format.

CD27 and CD40 costimulatory molecules and TILs expressing activation marker CD38 in the tumour were also correlated with patient survival. Mice depleted of mature B cells and transplanted with murine ...

For example, some strategies activate a patient’s own NK cells ... In one case, such allogeneic NK cells are engineered with a B cell-targeting/depleting monoclonal antibody (mAb) as a treatment ...

Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078, United States Oklahoma Center for Respiratory and Infectious Diseases, Oklahoma State ...