Instead, more cells decided to turn into ectoderm tissue, the type that eventually gives rise to our nervous system. This study shows that glycolysis helps activate key signaling pathways (Wnt ...

An increasing array of B-cell targeting approaches may aid clinicians in managing the cycles and flares of lupus, according ...

The role of EGFR in KRASG12D-driven tumorigenesis was studied using mouse CRC organoids with KRAS-APC-TP53 mutations and ...

APRIL plays a critical role in B-cell activation and IgA class switching, particularly in mucosal tissues. Blocking this pathway addresses the root cause of IgAN by diminishing the production of ...

The authors present an important set of data implicating ETFDH as an epigenetically suppressed gene in cancer with tumor suppressive functions. The evidence is solid, with the authors demonstrating ...

Researchers at the Tohoku University Graduate School of Medicine have uncovered a key primary step in the hepatic ERK pathway ...

In regenerative science, B7-33's potential to influence fibroblast activity and collagen turnover suggests possible implications for tissue repair and wound healing. Given that fibrosis is often a ...

“Whatever went up in TREM2-mid microglia, went down in TREM2-high cells,” Haass said. For example, metabolites reflecting glycolysis, glucose uptake ... “At what point in the disease is activation of ...

The concentration of phagocytes is held constant at 25 X 10 6 except in panel b. When the studies ... fact that whereas glycolysis and lactate production were normal in cells from patients with ...