An increasing array of B-cell targeting approaches may aid clinicians in managing the cycles and flares of lupus, according ...

The role of EGFR in KRASG12D-driven tumorigenesis was studied using mouse CRC organoids with KRAS-APC-TP53 mutations and ...

APRIL plays a critical role in B-cell activation and IgA class switching, particularly in mucosal tissues. Blocking this pathway addresses the root cause of IgAN by diminishing the production of ...

The authors present an important set of data implicating ETFDH as an epigenetically suppressed gene in cancer with tumor suppressive functions. The evidence is solid, with the authors demonstrating ...

Researchers at the Tohoku University Graduate School of Medicine have uncovered a key primary step in the hepatic ERK pathway ...

Deficiency: If you have a vitamin B12 deficiency you will feel tired or weak, pale skin, loss of appetite, infertility and ...

A new class of molecules capable of killing the cancer cells that are refractory to standard treatments and responsible for recurrence has just been developed. This crucial advance in the fight ...