An increasing array of B-cell targeting approaches may aid clinicians in managing the cycles and flares of lupus, according ...

The aberrant activation of B cells plays a central role in the pathogenesis of various autoimmune diseases and B-cell lymphomas. Now, Honigberg and colleagues describe an orally available ...

Instead, more cells decided to turn into ectoderm tissue, the type that eventually gives rise to our nervous system. This study shows that glycolysis helps activate key signaling pathways (Wnt ...

More information: Hongxing Shen et al, HIF1α-regulated glycolysis promotes activation-induced cell death and IFN-γ induction in hypoxic T cells, Nature Communications (2024). DOI: 10.1038 ...