neurofilament-medium and neurofilament-high. In axons, parallel neurofilaments form a nematic liquid-crystal hydrogel with network structure arising from interactions between the neurofilaments ...

Neurofilament proteins are the major scaffolding proteins of axons. On neuronal damage ... of early neurological deterioration than either tau or amyloid." The study was published online November ...

As the KLC1-negative animals aged, they exhibited axonal degeneration in the corpus callosum and anterior commissure, as well as increased neurofilament ... tau troubles. A panel of antibodies to ...

They found that multisynthase complex p43 (MSC p43) is required for the assembly of neurofilaments, which undergird axon stability. First author Xiaodong Zhu, principal investigator Jiawei Zhou, and ...

The protein, called neurofilament light or NfL for short, lends structural support to axons, the tendrils that send messages between brain cells. Levels of NfL peak on average at 10 times the ...