Lysosomes play a vital role in maintaining cellular health by clearing debris and supporting processes like autophagy. Lysosome impairment contributes to many diseases, including Alzheimer's ...

Recently, a new class of therapeutics that disable the neonatal Fc receptor (FcRn), which protects IgG from degradation, has emerged to treat IgG-mediated autoimmune disease. 4,5 Here, we review ...

March 26, 2025 (GLOBE NEWSWIRE) -- Optinose (NASDAQ:OPTN), a pharmaceutical company focused on patients treated by ear, nose and throat (ENT) and allergy specialists, today reported financial ...

In order for the degradation of cellular components through autophagy to occur, they must first be recognised as waste. This is done by receptor and other adapter molecules. However, it was ...

Get Instant Summarized Text (Gist) A 2016 bird flu variant was found to be one mutation away from binding to human receptors, highlighting the potential for avian influenza to adapt to humans. The ...

Optinose, Inc. (NASDAQ: OPTN)’s sale to Paratek Pharmaceuticals. Under the terms of the proposed transaction, Paratek will acquire Optinose for $9.00 per share in cash, plus up to $5.00 per ...

We sell different types of products and services to both investment professionals and individual investors. These products and services are usually sold through license agreements or subscriptions ...

In recent years, CAR-T cell immunotherapy (using chimeric antigen receptors) has revolutionized the fight against cancer. In combination with other tools (chemotherapy, radiotherapy), this new ...

The expression of E50K OPTN led to defective autophagy and RGC cell death. It also increased ROS levels through an unknown mechanism. Notably, antioxidant treatment prevented RGC death, indicating ...