Role of the RAAS in the Pathophysiology of Heart Failure ACE inhibitors have no effect on angiotensin II formed by alternate pathways. In contrast, ARBs would be expected to inhibit the biologic ...

Research that focused on blocking the renin-angiotensin system (RAS ... In addition to inhibiting the conversion of AT-I to AT-II, ACE inhibitors block the degradation of bradykinin via kininase ...

Beijing Tide Pharmaceutical Co., Ltd., a subsidiary of Sino Biopharmaceutical Limited (1177.HK), has achieved a milestone in developing its first-in-class analgesic drug (research code: TRD205), a ...

Angiotensin II doesn’t just affect blood pressure—it also plays a role in brain function, potentially influencing mood and ...

STOCKHOLM, SE / ACCESS Newswire / May 6, 2025 / Vicore Pharma Holding AB (STO:VICO) ("Vicore"), unlocking the potential of a new class of drug candidates, angiotensin II type 2 receptor agonists ...

STOCKHOLM, SE / ACCESS Newswire / May 6, 2025 / Vicore Pharma Holding AB (STO:VICO) ("Vicore"), unlocking the potential of a new class of drug candidates, angiotensin II type 2 receptor agonists (ATRA ...

Travere Therapeutics, Inc. today announced that the U.S. Food and Drug Administration (FDA) has accepted its supplemental New Drug Application (sNDA) for traditional approval of FILSPARI (sparsentan) ...

Special Report: Dimerix has received the upfront payment of US$30 million (~A$48m) from Amicus Therapeutics after signing an ...

Dimerix’s Angiotensin II Type 1 Receptor (AT1R) & Chemokine Receptor 2 (CCR2) Targets for Inflammatory Nephrosis (ACTION) trial is a Phase 3, multi-centre, randomised, double-blind, placebo-controlled ...

The early impact of gestational diabetes, hypertensive disorders of pregnancy, and obesity appears to grow as kids age.