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This limited availability of nutrients, including glucose, oxygen and amino acids, drives nutrient stress in the TME ... like nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry ...
and fecal metabolite profiles were assessed using liquid chromatography-tandem mass spectrometry. Analyses adjusted for diet, smoking, physical activity, and other covariates. The researchers ...
Using a combination of co-immunoprecipitation, mass spectrometry, and point mutant studies, specific amino acids that are required for compound-induced PPI and subsequent degradation of SMARCA2 were ...
The new method, developed over the last eight years and detailed in the journal Nature Protocols is called DiBT-MS (Direct Analysis of Biotransformations with Mass Spectrometry). Sabine Flitsch, Chair ...
McKenzie (Imperial), uses mass spectrometry for its innovative approach. This enabled the researchers to identify specific metabolic products of bacteria directly in tissue and stool samples.
It builds on an existing technology called DESI-MS (Desorption Electrospray Ionization Mass Spectrometry), a powerful tool that allows scientists to analyze complex biological samples without the ...
Other methods, like regular mass spectrometry, can detect hundreds of molecules but don't work on intact samples, so researchers can't see how the biomolecules are oriented. One promising technique – ...
Typically, plant-based foods have more varied levels of indispensable amino acids that the body can use, as compared to animal-sourced foods, so they are of particular concern in vegan diets.
Bruker and RECIPE are pioneering the high-throughput ‘chrom-free’ ClinDART triple-quad MS platform for robust and cost-effective therapeutic drug monitoring assays MUNICH, April 16, 2025 ...
Metabolomic approaches including Fourier- transform infrared (FT-IR) spectroscopy and Electrospray ionisation mass spectrometry (ESI-MS ... resistance in plants against pathogen stress. Poster ...