The third is the alternative pathway ... Brenner: There are three pathways of complement activation. Each of those three pathways has a unique enzyme that initiates the complement cascade.

PTX3 is also involved in the regulation of the lectin pathway (LP) through interactions with MBL and Ficolins. In addition, PTX3 recognizes regulators of complement activation, in particular the most ...

AChR blocking and antigenic modulation trigger complement activation in MG. In addition to the classical pathway, the role of the activated alternative pathway in MG pathology requires further ...