Taking multiple blood pressure medications but still have high readings? Aldosterone excess might be sabotaging your ...

What Is an Aldosterone Test? If you’re having any blood pressure problems, your doctor might order an aldosterone test. An aldosterone test measures the amount of the hormone aldosterone in your ...

Aldosterone, a hormone produced by the triangular adrenal glands, might be the key target. In the observational study, researchers analyzed health data from 3,680 people with chronic kidney ...

Lorundrostat, a selective aldosterone synthase inhibitor, significantly reduced 24-hour systolic blood pressure in individuals with uncontrolled and treatment-resistant hypertension, according to ...

A novel treatment, an aldosterone synthase inhibitor, safely and consistently lowered blood pressure in individuals with ...

Mineralys Therapeutics, Inc.'s lorundrostat shows promise for treating aldosterone-driven hypertension with FDA approval by ...

The emerging role of aldosterone in hypertension and cardiovascular diseases has prompted a renewal of interest in therapeutic approaches designed to interfere with the action of this ...

Perspectives from Keith Churchwell, MD, FAHA Keith C. Ferdinand, MD CHICAGO — The investigational aldosterone synthase inhibitor lorundrostat effectively lowered 24-hour BP for adults with well ...

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Dysregulated aldosterone production, sometimes driven by obesity, can cause hypertension. Targeted therapies that directly reduce aldosterone synthesis may help treat challenging cases of ...

Aldosterone is a steroid hormone made in the outer part of your adrenal glands. This hormone helps your body maintain the right levels of fluid and sodium in your body and get rid of extra ...

New drug lorundrostat shows promising results in lowering blood pressure for patients with resistant hypertension.