DelveInsight's Chronic Kidney Disease pipeline report depicts a robust space with 75+ active players working to develop 80+ ...

A novel treatment, an aldosterone synthase inhibitor, safely and consistently lowered blood pressure in individuals with ...

Mineralys Therapeutics, Inc.'s lorundrostat shows promise for treating aldosterone-driven hypertension with FDA approval by ...

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Most people assume that when blood pressure stays high despite medication, it’s due to stress or an incorrect dose. But resistant hypertension is a specific clinical condition. It means one’s blood ...

The following is a summary of “Potassium binders in clinical practice: understanding potassium binder use in contemporary Swedish healthcare—the DEMONSTRATE database,” published in the April 2025 ...

In a country where nearly 1 in 3 adults silently battles high blood pressure , the need for regular blood pressure monitoring ...

A novel treatment for hard-to-control high blood pressure has shown strong results in a major global clinical trial. The Phase 3 Launch-HTN study found that lorundrostat, an aldosterone synthase ...

A new medication called lorundrostat has shown strong potential as a treatment for people with uncontrolled or resistant high ...

Vitamin D also helps blood vessels work better. It may help them stay flexible and relaxed. When blood vessels are relaxed, ...

Renin content and mRNA were 77% and 65±5% of WT. Plasma aldosterone (in picograms per mL) was also significantly reduced (420±36 in β1/β2ADR −/− versus 692±59 in WT). A low-salt diet (0.03%) for 1 ...

2 Moreover, the hazard ratio (1.34) for heart failure hospitalization and for atrial fibrillation (1.37) raised with renin suppression and higher plasma aldosterone levels, respectively. See related ...