Abstract: Alternative splicing is a process by which the same DNA sequence is used to assemble different proteins, called protein isoforms. Alternative splicing works by selectively omitting some of ...

Although alternative splicing is a notable addition to '-omic'-based molecular profiles in prostate cancer, further studies are required to correlate the expression of specific splice variants ...

Initially, hit molecules were evaluated via qPCR for dose responsiveness and to confirm the desired splicing activity. Once the desired splicing pattern was confirmed, SMN protein levels were assessed ...

Tau undergoes alternative splicing which generates six isoforms in the human brain, due to inclusion/exclusion of exons 2, 3 and 10. Dysregulation of the splicing process of tau exon 10 is sufficient ...

College of Medical Laboratory Science and Technology, Harbin Medical University, Daqing, PR China. (J.M., Z.M., S. Wen, L.O., L.Z., Y.C., X. Zheng, X. Zhu, Z.W., D.Z ...

Alternative pre-mRNA splicing is a fundamental mechanism of post-transcriptional gene regulation that creates lineage-specific functional diversity in the proteome. Although heart-specific alternative ...

Abstract: A key challenge of image splicing detection is how to localize integral tampered regions without false alarm. Although current forgery detection approaches have achieved promising ...

Lignin has potential as a reinforcing filler and to become an alternative to carbon black in the rubber industry. This is because it is formed from cheaper materials with abundant annually renewable ...

A recent collaboration between the Wildlife Conservation Society Canada (WCS) and Tr’ondëk Hwëch’in, a First Nation in the Yukon, offers an alternative approach, in which Western and ...

PITTSBURGH -- In the blink of an eye, the Pittsburgh Steelers are just over a week away from the beginning of Organized Team Activities (OTAs). Following rookie minicamp, this is the first big ...

When it comes to web browsing, speed and reliability can make or break your day. Both Microsoft Edge and Google Chrome are robust and capable web browsers built on the same core technology, offering ...

There, a parent-led group called OK to Delay had organized an “Alternative Device Fair” for families who wanted to learn about different kinds of phones that were intentionally limited in ...