Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers have discovered that one type of stem cell thought to be dormant may play a more ...

Neural organoids and 3D spheroids are a fast-evolving technology with enormous potential for studying brain development and ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release ...

New tissue-derived organoid model: A next-generation organoid model, composed of three liver cell types – adult hepatocytes, cholangiocytes, and liver mesenchymal cells – reconstructs the liver ...

Cells change their metabolic profiles in response to underlying gene regulatory networks, but how can alterations in metabolism encode specific transcriptional instructions? Here, we show that forcing ...

CXCR4-OE, claudin-2-OE, and Linc-ZNF469-3-OE MDA-MB-231 cells demonstrate the highest invasion and most prominent localization in bone, liver, and lung respectively. Organoid cells derived from a ...

Over the last decades, several innovations have advanced the understanding of human biology and diseases. From the development of induced pluripotent stem ...