Vitamin D deficiency directly causes erectile dysfunction by increasing superoxide and reducing protective SLPI levels, as ...

While superoxide is typically recognized for its destructive effects on DNA, proteins, and other cellular molecules, this study highlights a novel, constructive role for the molecule in biosynthesis.

Epidemiological studies suggest a relationship between vitamin D deficiency and erectile dysfunction (ED). We hypothesized that vitamin D deficiency or vitamin D receptor (VDR) knockout causes ED and ...

What we discovered is that all of these different pathogenic mechanisms do reflect a single hyperglycemia-induced process and that this single unifying process is the overproduction of superoxide ...

The internal workshop generates superoxide, which is then transported via the tunnel to the surface workshop, where it catalyzes a series of radical reactions that convert substrates into the ...