NMDA receptors (NMDARs) are glutamate-gated ion channels that are present at most excitatory mammalian synapses. The four GluN2 subunits (GluN2A–D) contribute to four diheteromeric NMDAR subtypes that ...
Cold Spring Harbor, NY – Structural biologists at Cold Spring Harbor Laboratory (CSHL) in collaboration with colleagues at Emory University have determined the molecular structure of a key portion, or ...
Together with the AMPA receptors (AMPARs) and kainate receptors, the NMDARs belong to the superfamily of ionotropic glutamate receptors (iGluRs), which mediate excitatory communication between neurons ...
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